Tuesday 12 November 2013

pathologic characteristics of Alzheimer

Difficulties in diagnosis, when it is based solely on clinical and, as we have seen, is not unique to this disease results in a confirmation of
Alzheimer's disease by autopsy only in the majority of cases (85 to 90% of cases)
The pathologic characteristics of Alzheimer autopsy material in relation to the presence of euro tangles within neurons scars and neuritis plaque myeloid protein in the extracellular space.
Addition to the method to assess the clinical examination and the method anatomy for pathological diagnosis of Alzheimer's disease, have left the genetic and brain imaging evidence.for more details click here 
http://www.mamapearl.com/forum/thread/325/the-lenses-on-the-sea-yes-or-no/
 The genetic evidence studying the possibility of the defective gene Apo-E, but are not yet fully available and not well established.
 Now, in relation to Alzheimer's disease euro imaging obtained by PET and SPECT by some typical alterations of the disease are relatively well established
 For example a marked reduction of medial temporal lobe and hippocampus which can be up-rated by Nuclear Magnetic Resonance. Regarding functional euro imaging, there is a standard
Low-functioning (hypo metabolism) in the tem region characteristic of this disease
Therefore, currently, PET or SPECT are the most reliable tests to support clinical suspicion of the disease.for information 
http://www.flickclub.com/forum/thread/377/the-lenses-on-the-sea-yes-or-no/
TO CT imaging features of this disease consist of an increase in the volume of the lateral ventricles, third ventricle with size up to 2 times normal size associated with the enlargement of the cortical sulci. But those changes are not unique to Alzheimer's disease, can be found in other states or even dementia in normal aging.


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