Difficulties in diagnosis, when it is based solely
on clinical and, as we have seen, is not unique to this disease results in a
confirmation of
Alzheimer's disease by autopsy only in the majority
of cases (85 to 90% of cases)
The pathologic characteristics of Alzheimer autopsy
material in relation to the presence of euro tangles within neurons scars and neuritis
plaque myeloid protein in the extracellular space.
Addition to the method to assess the clinical
examination and the method anatomy for pathological diagnosis of Alzheimer's
disease, have left the genetic and brain imaging evidence.for more details click here
http://www.mamapearl.com/forum/thread/325/the-lenses-on-the-sea-yes-or-no/ |
The genetic
evidence studying the possibility of the defective gene Apo-E, but are not yet
fully available and not well established.
Now, in
relation to Alzheimer's disease euro imaging obtained by PET and SPECT by some
typical alterations of the disease are relatively well established
For example a
marked reduction of medial temporal lobe and hippocampus which can be up-rated
by Nuclear Magnetic Resonance. Regarding functional euro imaging, there is a
standard
Low-functioning (hypo metabolism) in the tem region characteristic
of this disease
Therefore, currently, PET or SPECT are the most
reliable tests to support clinical suspicion of the disease.for information
http://www.flickclub.com/forum/thread/377/the-lenses-on-the-sea-yes-or-no/ |
TO CT imaging features of this disease consist of an
increase in the volume of the lateral ventricles, third ventricle with size up
to 2 times normal size associated with the enlargement of the cortical sulci.
But those changes are not unique to Alzheimer's disease, can be found in other
states or even dementia in normal aging.